Arizona State University College of Liberal Arts and Sciences

MBB 343/BIO 343 figure

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Genetic Engineering and Society

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MBB 343/BIO 343, Fall 2007, 4 credit hours
Arizona State University, Main Campus

Lecture: TTH 12:15-1:30, LSE 106
Lab: T or W 8:40-11:30 or 1:40-4:30 pm, or W 5:40-8:30 pm
in LSE-S79 and LSE-244


The required textbook for the course is B.R. Glick and J.J. Pasternak (2003) Molecular Biotechnology: Principles and Applications of Recombinant DNA, third edition.  Use of a “clicker” in the classroom is required as well.  Both are available in the ASU bookstore.  Additional materials are on this website and/or are posted on the Blackboard site http://myasucourses.asu.edu, which is accessible to students registered in the class.


Material at this site may be used freely by others as long as the source of the information is acknowledged.  Contact the appropriate web master to learn about the rules of using materials contained at other web sites that are referred to at this site.


CONTENTS

INSTRUCTORS

AIMS AND EXPECTATIONS

EXPECTED BACKGROUND, AND TEXTBOOK INFO

SCHEDULE OVERVIEW

DETAILED LECTURE SCHEDULE


ADDITIONAL MATERIALS, LECTURE PART:

HISTORICAL PERSPECTIVE
Heredity and the gene

INTRODUCTION TO BIOTECHNOLOGY

DNA, RNA AND PROTEIN SYNTHESIS (Chapter 3)
Structure and function of DNA
RNAs
Protein synthesis
RNA editing

CHEMICAL SYNTHESIS, SEQUENCING, AND AMPLIFICATION OF DNA (Chapter 5)
DNA sequencing
Polymerase Chain Reaction (PCR)

DIRECTED MUTAGENESIS AND PROTEIN ENGINEERING (Chapter 8)
Protein engineering of laundry detergent
Combinatorial mutagenesis

VACCINES (Chapter 11)
Vaccine production
A new generation of rabies vaccine
Vaccine production in plants
AIDS

ANTIBIOTICS AND PROTEINS MADE BY BACTERIA (Chapter 12)
Antibiotics
Milk production

BIOREMEDIATION (Chapter 13)
Biotransformation of toxic wastes to harmless products

BIOLOGICAL INSECT CONTROL (Chapter 15)
Pesticidal proteins
Other ways of biocontrol

PLANT GENETIC ENGINEERING: METHODOLOGY (Chapter 17)
Plant transformation

PLANT GENETIC ENGINEERING: APPLICATIONS (Chapter 18)
"Pharming" and "plantibodies"
Reversible male sterility in plants
Antisense RNA
Agricultural applications in developing countries

TRANSGENIC ANIMALS (Chapter 19)
Human proteins
Dolly and Polly
Fish farming

HUMAN MOLECULAR GENETICS (Chapter 20)
The human genome initiative
Use of genomic data
Genetic disorders
Restriction fragment length polymorphism (RFLP)
Genetic screening
Forensic applications
Other applications of DNA fingerprinting

REGULATORY AND ETHICAL ASPECTS (Chapter 21)
Ethical considerations
Stem cell research
The release of genetically engineered organisms into the environment

BIOTECHNOLOGY INVENTIONS (Chapter 22)
Patent protection of living organisms
Gene technology laws in other countries

ADDITIONAL MATERIALS
Misuse of gene technology
Careers in biotechnology

LABORATORY PART:

AIMS AND EXPECTATIONS

LAB SCHEDULE OVERVIEW

SCHEDULE


Instructors | Aims
Lecture Part: Schedule | Expected Background & Textbook Info | Historical Perspective
Intro to Biotechnology | DNA, RNA and Protein Synthesis | Chemical Synthesis, Sequencing, and Amplification of DNA |
Directed Mutagenesis and Protein Engineering | Vaccines | Antibiotics & Proteins | Bioremediation |
Microbial Insecticides | Plant Genetic Engineering: Methodology | Plant Genetic Engineering: Applications | Transgenic Animals
Human Molecular Genetics | Regulatory & Ethical Aspects | Biotech Inventions | Additional Materials
Lab Part: Aims and Expectations | Schedule

Center for Bioenergy & Photosynthesis

Arizona State University

Box 871604

Room PSD 209

Tempe, AZ 85287-1604

 

16 August 2007

phone: (480) 965-1963

fax: (480) 965-2747

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