Welcome to the
Genetic Engineering and Society
web site!
MBB 343/BIO 343, Fall 2008, 4 credit hours
Arizona State University, Main Campus
Lecture: TTH 12:00-1:15, Lattie Coor Hall L1-74
Lab:
M 2:00-5:00 pm, T 8:45-11:35 am, or 1:30-4:20 pm, or 6:00-8:50 pm,
W 8:45-11:35 am, or 2:00-4:50 pm
in LSE-S79 and LSE-244
The required textbook for the course is B.R. Glick and J.J. Pasternak (2003) Molecular
Biotechnology: Principles and Applications of Recombinant DNA, third edition. Use
of a “clicker” in the classroom is required as well. Both are
available in the ASU bookstore. Additional materials are on this website
and/or are posted on the Blackboard site http://myasucourses.asu.edu,
which is accessible to students registered in the class.
Material at this site may be used freely by others as long as the source of the
information is acknowledged. Contact the appropriate web master to learn
about the rules of using materials contained at other web sites that are referred
to at this site.
CONTENTS
- INSTRUCTORS
- AIMS AND EXPECTATIONS
EXPECTED BACKGROUND, AND TEXTBOOK INFO
SCHEDULE OVERVIEW
DETAILED LECTURE SCHEDULE
- ADDITIONAL MATERIALS, LECTURE PART:
- HISTORICAL PERSPECTIVE
- Heredity and the gene
- INTRODUCTION TO BIOTECHNOLOGY
- DNA, RNA AND PROTEIN SYNTHESIS (Chapter
3)
- Structure and function of DNA
- RNAs
- Protein synthesis
- RNA editing
- CHEMICAL SYNTHESIS, SEQUENCING, AND AMPLIFICATION
OF DNA (Chapter 5)
- DNA sequencing
- Polymerase Chain Reaction (PCR)
- DIRECTED MUTAGENESIS AND PROTEIN ENGINEERING
(Chapter 8)
- Protein engineering of laundry detergent
- Combinatorial mutagenesis
- VACCINES (Chapter 11)
- Vaccine production
- A new generation of rabies vaccine
- Vaccine production in plants
- AIDS
- ANTIBIOTICS AND PROTEINS MADE BY BACTERIA
(Chapter 12)
- Antibiotics
- Milk production
- BIOREMEDIATION (Chapter 13)
- Biotransformation of toxic wastes to harmless products
- BIOLOGICAL INSECT CONTROL (Chapter 15)
- Pesticidal proteins
- Other ways of biocontrol
- PLANT GENETIC ENGINEERING: METHODOLOGY
(Chapter 17)
- Plant transformation
- PLANT GENETIC ENGINEERING: APPLICATIONS
(Chapter 18)
- "Pharming" and "plantibodies"
- Reversible male sterility in plants
- Antisense RNA
- Agricultural applications in developing countries
- TRANSGENIC ANIMALS (Chapter 19)
- Human proteins
- Dolly and Polly
- Fish farming
- HUMAN MOLECULAR GENETICS (Chapter 20)
- The human genome initiative
- Use of genomic data
- Genetic disorders
- Restriction fragment length polymorphism (RFLP)
- Genetic screening
- Forensic applications
- Other applications of DNA fingerprinting
-
- REGULATORY AND ETHICAL ASPECTS (Chapter
21)
- Ethical considerations
- Stem cell research
- The release of genetically engineered organisms into the environment
- BIOTECHNOLOGY INVENTIONS (Chapter
22)
- Patent protection of living organisms
- Gene technology laws in other countries
- ADDITIONAL MATERIALS
- Misuse of gene technology
- Careers in biotechnology
LABORATORY PART:
AIMS AND EXPECTATIONS
LAB SCHEDULE OVERVIEW
SCHEDULE
Instructors | Aims
Lecture Part: Schedule | Expected Background & Textbook Info | Historical Perspective
Intro to Biotechnology | DNA, RNA and Protein Synthesis | Chemical Synthesis, Sequencing, and Amplification of DNA |
Directed Mutagenesis and Protein Engineering | Vaccines | Antibiotics & Proteins | Bioremediation |
Microbial Insecticides | Plant Genetic Engineering: Methodology | Plant Genetic Engineering: Applications | Transgenic Animals
Human Molecular Genetics | Regulatory & Ethical Aspects | Biotech Inventions | Additional Materials
Lab Part: Aims and Expectations | Schedule
